Product Overview
(S)-(+)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine (CAS No. 90761-62-9) is a chiral derivatization agent and HPLC resolving reagent, commonly used in enantiomeric separation and analytical chemistry applications. This high-purity compound is a valuable tool in pharmaceutical research for determining the enantiomeric excess (ee) of chiral amines, amino acids, and other optically active compounds. Suitable for advanced analytical and laboratory-scale use, it is supplied with strict quality control to ensure reproducibility in chiral resolution studies.
Product Information
- Product Name: (S)-(+)-N-(3,5-Dinitrobenzoyl)-α-phenylglycine
- Synonyms: (S)-DNB-PG, (S)-(+)-N-(3,5-Dinitrobenzoyl)phenylglycine
- CAS Number: 90761-62-9
- Molecular Formula: C₁₅H₁₁N₃O₇
- Molecular Weight: 345.27 g/mol
- Optical Rotation: [α]D²⁰ approximately +XX° (c=1, MeOH)*
(* Exact value may vary depending on solvent and concentration; specific data available on request.)
Specifications
- Appearance: Yellow to off-white crystalline powder
- Purity (HPLC): ≥ 98% (higher purity available upon request)
- Chiral Purity (ee): ≥ 99% (chiral HPLC confirmed)
- Solubility: Soluble in polar organic solvents (methanol, DMF, DMSO)
- Storage Temp.: 2–8 °C, protected from light and moisture
- Residual Solvents: Meets ICH guidelines (if applicable)
Physical & Chemical Properties
- Melting Point: ~180-185 °C (decomposition may occur)
- UV/Vis: Absorbs strongly in the UV range (λmax ~250-280 nm)
- Stability: Stable in solid form; long-term storage in inert atmosphere recommended
Applications
- Chiral Derivatization Reagent: Used for HPLC resolution of enantiomeric amines, amino acids, and other chiral compounds via diastereomer formation.
- Asymmetric Synthesis Research: Employed in studies of stereoselective reactions and catalyst screening.
- Quality Control in Pharmaceuticals: Assists in ensuring enantiomeric purity of APIs and intermediates.
- Academic & Industrial Research: Supports method development in analytical and medicinal chemistry.
(This product is for laboratory use only—not for drug, food, or medical applications.)
Storage
- Recommended Storage: 2–8 °C in a tightly sealed container under nitrogen/vacuum.
- Handling: Protect from light, moisture, and prolonged air exposure to prevent degradation.
Packaging & Supply
- Standard Packaging: Glass vials (100 mg–1 g) or amber bottles (5–25 g).
- Bulk Quantities: Kilo-scale production available with custom purity specifications.
- Special Formats: Pre-weighed aliquots or solution-based formulations (on request).
Documentation
- Provided with Shipment:
- Certificate of Analysis (CoA, includes HPLC, NMR, and chiral purity data)
- Safety Data Sheet (SDS)
- Method development support available upon inquiry.
