TPN171 CAS .1229018-87-4
TPN171 is a highly potent PDE5 inhibitor, demonstrating sub-nanomolar activity against PDE5 along with excellent selectivity over PDE6. It is currently under clinical development for the treatment of pulmonary arterial hypertension (PAH). In preclinical studies, TPN171 has shown a longer duration of action compared to sildenafil, supporting its potential for once-daily oral administration in clinical use.
Technical Data
| Related CAS | 1229018-87-4 (free base) 2258665-03-9 (acetate) 2258665-04-0 (mesylate) 2258665-07-3 (HCl) |
| Synonym | TPN171; TPN-171; TPN 171; |
| Chemical Name | N-(3-(5,6-Diethyl-4(3H)-pyrimidone-2-yl)-4-n-propoxyphenyl)-2-(4-methylpiperazin-1-yl)acetamide |
| Chemical Formula | C24H35N5O3 |
| Molecular Weight | 441.58 |
| Appearance | White powder |
| Purity | 99%min |
| Storage Condition | Store in a sealed container at room temperature. |
| Shelf Life | >3 years if stored properly |
| Supply Capacity | This product is supported by kilogram-scale production capacity, delivering ≥99% purity (HPLC). We maintain regular production and buffer stock, enabling reliable supply and faster delivery for ongoing customer needs. |
Related Products
Explore More Solutions
N-Benzylguanidine hydrochloride CAS No. 1197-49-5
N-Benzylguanidine hydrochloride CAS No. 1197-49-5 is a mature fine chemical with a well-established process, ensuring consistent quality and reliable supply. We offer standard packaging (bottles or drums) with a flexible MOQ starting from small quantities, and scalable production to support larger customer demands.
View Details
1-(4-Methoxyphenyl)-2-benzylaminopropane CAS 43229-65-8
View Details