Product Overview
2-Hydroxy-2-phenyl-cyclohexanecarboxylic acid is a high-purity pharmaceutical intermediate featuring a sterically defined cyclohexane core with strategically positioned hydroxyl and carboxyl functional groups. Its rigid molecular architecture makes it particularly valuable for constructing spatially constrained pharmacophores in medicinal chemistry applications.
Product Information
- IUPAC Name: 2-Hydroxy-2-phenylcyclohexane-1-carboxylic acid
- CAS Number: 15733-89-8
- Molecular Formula: C₁₃H₁₆O₃
- Molecular Weight: 220.27 g/mol
- Stock Status: In stock and available for immediate shipment
Physical & Chemical Properties
| Property | Value/Description |
|---|---|
| Melting Point | 186-190°C |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water |
| Density | ~1.25 g/cm³ (est.) |
| Optical Rotation | [α]D²⁰ = +15° to +18° (c=1, in methanol) |
| pKa | ~3.2 (carboxyl), ~15.0 (hydroxyl) |
| Stability | Stable under recommended storage conditions |
Specifications
| Parameter | Specification | Test Method |
|---|---|---|
| Appearance | Light yellow crystalline powder | Visual |
| Purity (HPLC) | ≥98.0% | HPLC |
| Water Content | ≤0.5% | Karl Fischer |
| Heavy Metals | ≤10ppm | ICP-MS |
Applications
- Key intermediate in the synthesis of sterically hindered bioactive compounds
- Chiral building block for pharmaceutical development
- Versatile scaffold for structure-activity relationship (SAR) studies
- Precursor for:
- CNS-targeting drug candidates
- Conformationally restricted analogs
- Chelating ligand systems in asymmetric catalysis
Packaging & Supply
- Standard Packaging:
- 1-10kg: Double-layer aluminum foil bags with PE liner + desiccant
- ≥25kg: Sealed fiberboard drums with moisture barrier
- MOQ: 1kg
- Delivery: Ready to ship within 24 hours after order confirmation
- Sample Available: Small quantities available for R&D evaluation
Storage
Store in sealed original packaging at 2-8°C. Protect from moisture and light.
Documentation
Provided with each shipment:
- Certificate of Analysis
- Material Safety Data Sheet
- HPLC chromatogram (upon request)
Order Information
Orders accepted 24/7 through our online system or via email. Our customer service team is available to assist with urgent requests and provide real-time stock verification.
